Ultrasound-guided perineural tibial nerve dextrose injection for plantar fasciitis: a case series highlighting safety and efficacy

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Guntur Darmawan, Alif Noeriyanto Rahman, Stanley King Hei Lam, Faisal Parlindungan, Laniyati Hamijoyo, Tolga Ergonenc

2026 Folia Medica Vol. 68 Issue 2 Article Cited by 0 SDG 3SDG 17 Quartile

Abstract

Treatments for plantar fasciitis are often unsatisfactory. Dextrose exerts an analgesic effect through inhibiting transient receptor potential vanilloid receptor 1 (TRPV1)-mediated neuroinflammation. We reported the effectiveness of ultrasound-guided perineural tibial nerve (TN) 5% dextrose water (D5W) injection using the hydrodissection technique in treating plantar fasciitis. Two patients, a 52-year-old woman and a 60-year-old overweight man, presented with chronic left heel pain. Both had tried various treatments without sustained improvement. Ultrasound demonstrated an increase in the thickness of the plantar fascia, confirming the diagnosis of plantar fasciitis. Due to painful experience during previous intervention, they sought a less painful and more durable treatment option. We performed perineural TN ultrasound-guided D5W injection using the hydrodissection technique in two sessions, resulting in significant pain reduction and a less painful injection experience. A one-month follow-up showed sustained pain relief. Perineural TN D5W injection using the hydrodissection technique appears to be an effective treatment option for plantar fasciitis. Copyright by authors.

Affiliations

Department of Internal Medicine, Faculty of Medicine, Krida Wacana Christian University, Jakarta, Indonesia; Medical Faculty, Universitas Pendidikan Indonesia, Bandung, Indonesia; Faculty of Medicine, The University of Hong Kong, Hong Kong; Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong; The Board of Clinical Research, The International Association of Musculoskeletal Medicine, Hong Kong; The Board of Clinical Research, The Hong Kong Institute of Musculoskeletal Medicine, Hong Kong; Division of Rheumatology, Department of Internal Medicine, Faculty of Medicine, University of Indonesia, Jakarta, Indonesia; Division of Rheumatology, Department of Internal Medicine, Faculty of Medicine, Universitas Padjadjaran, Bandung, Indonesia; Akyazi Hospital, Traditional and Complementary Medicine Unit, Sakarya, Turkey

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