Didi N. Illian, Lalu M. Irham, Fitri Deliana, Fiska M. Wardhani, Wirawan Adikusuma, Arini S. Al-Mustaqimah, Hayssam M. Ali, Refi Ikhtiari, Muhammad F. Lubis, Mohammad Basyuni
Context: Demographic forecasts suggest that new cancer cases may reach 35 million by 2050, underscoring the need for innovative, regionally tailored control strategies. Mangroves have yielded multiple potential anticancer compounds in recent years; however, no bibliometric investigation of their role has been conducted. Aims: To provide a bibliometric overview of research on anticancer activity from mangroves. Methods: Keywords related to anticancer activity and mangroves to search the Scopus database were used. VOSviewer and Biblioshiny were used for further analysis. Results: Eighty-seven studies on cancer-associated mangroves were identified, with an annual growth rate of 9.89%. Publications have increased since 2005, reaching a peak in 2020. The top five countries and organizations in productivity were China, India, Indonesia, Malaysia, and Thailand. The top five affiliations were Guangdong Medical University, Shanghai Jiao Tong University, Sun Yat-Sen University, Wuhan University, and Guangdong University of Technology. Wu X, Liu J, Basyuni M, and Tang X were the most prolific authors. Five primary study themes emerged: antineoplastic activity, mangroves, apoptosis, cell proliferation, and protein expression. Conclusions: Recent results indicate a growing interest in the anticancer potential of mangrove bioactive chemicals, which regulate multiple protein expression signaling pathways. This increase in study emphasizes the significance of mangrove bioactive compounds in cancer research. © 2025 Journal of Pharmacy & Pharmacognosy Research
Department of Pharmacy, Faculty of Mathematics and Natural Sciences, Universitas Syiah Kuala, Banda Aceh, Indonesia; Doctoral Program of Pharmaceutical Sciences, Faculty of Pharmacy, Universitas Gadjah Mada, Yogyakarta, Indonesia; Faculty of Pharmacy, Universitas Ahmad Dahlan, Yogyakarta, Indonesia; Department Pharmacy, School of Health and Clinical Sciences, University of Western Australia, Perth, WA, Australia; Faculty of Medicine, Universitas Pendidikan Indonesia, Bandung, Indonesia; Research Center for Vaccine and Drugs, National Research and Innovation Agency (BRIN), South Tangerang, Indonesia; Faculty of Public Health, Universitas Sumatera Utara, Medan, Indonesia; Center of Excellence for Mangrove, Universitas Sumatera Utara, Medan, Indonesia; Department of Botany and Microbiology, College of Science, King Saud University, Riyadh, Saudi Arabia; Department of Biomedical Sciences, Faculty of Medicine, Universitas Prima Indonesia, Medan, 20118, Indonesia; Department of Pharmaceutical Biology, Faculty of Pharmacy, Universitas Sumatera Utara, Medan, Indonesia; Department of Forestry, Faculty of Forestry, Universitas Sumatera Utara, Medan, Indonesia
Research at a Glance
Register to unlock
Topics & SDG Alignment
Register to unlock
Collaboration
Register to unlock
Author Profile (Selected)
Register to unlock
References Overview
Register to unlock
Journal & Source
Register to unlock
Metadata & Integrity
Register to unlock