Lisna Anisa Fitriana, Mustika Fitri, Komarudin Komarudin, Afianti Sulastri
Introduction: Menopause is a condition where there is a decrease in the hormones estrogen and progesterone in women which causes a reduction in balance and cognition. It is known that Centella asiatica and aerobic exercise enhance cognitive function and physical appearance, but their combination in menopausal women is undetermined. This study aimed to evaluate the efficacy of Centella asiatica and aerobic exercise on estradiol, cognition, and balance in menopausal women. Materials and methods: The research design consisted of a 12-week pre- and post-test period. There were 48 menopausal women, with an average age of 53.25 years, served as research subjects. Twelve participants were assigned to the CA group (Centella asiatica, 2x500 mg/day), the AE group (aerobic exercise, 2x90 minutes/week), the CA-AE combination group (n=12), and the control group (n=12). Results: The findings demonstrated that the combination of CA-AE caused an increase in plasma estradiol (p=0.041). The Mann-Whitney test revealed that CA was predicted to have the greatest effect on semantic fluency (∆=4.44; p=0.001), forward digit span (∆=0.6; p=0.015), and backward digit span (∆=2.8; p=0.001). AE was expected to produce the greatest improvement in one-leg balance with eyes open (∆=34.1; p=0.003). In the meantime, the combination of CA-AE resulted in the most significant improvement in MoCA (∆=4.6; p<0.001), phonemic fluency (∆=1.8; p=0.004), and visual recall (∆=6.9; p<0.001). Conclusion: Centella asiatica and aerobic exercise have the potential to enhance plasma estradiol, cognition, and balance in postmenopausal women. A greater sample size will allow for more accurate results in future investigations. © 2024 Universiti Putra Malaysia Press. All rights reserved.
Program Study of Nursing, Faculty of Sport and Health Education, Universitas Pendidikan Indonesia, Bandung, 40154, Indonesia; Program Study of Sport Science, Faculty of Sport and Health Education, Universitas Pendidikan Indonesia, Bandung, 40154, Indonesia; Department of Sport Coaching Education, Faculty of Sport and Health Education, Universitas Pendidikan Indonesia, Bandung, 40154, Indonesia
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